Circulation AHA STATISTICAL UPDATE Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association Connie W. Tsao, MD, MPH, FAHA, Chair; Aaron W. Aday, MD, MSc, FAHA; Zaid I. Almarzooq, MB, BCH; Alvaro Alonso, MD, PhD, FAHA; Andrea Z. Beaton, MD, MS, FAHA; Marcio S. Bittencourt, MD, PhD, MPH, FAHA; Amelia K. Boehme, PhD, MSPH; Alfred E. Buxton, MD; April P. Carson, PhD, MSPH, FAHA; Yvonne Commodore-Mensah, PhD, MHS, RN, FAHA; Mitchell S.V. Elkind, MD, MS, FAHA; Kelly R. Evenson, PhD, MS, FAHA; Chete Eze-Nliam, MD, MPH; Jane F. Ferguson, PhD, FAHA; Giuliano Generoso, MD, PhD; Jennifer E. Ho, MD, FAHA; Rizwan Kalani, MD; Sadiya S. Khan, MD, MSc, FAHA; Brett M. Kissela, MD, MS, FAHA; Kristen L. Knutson, PhD; Deborah A. Levine, MD, MPH; Tené T. Lewis, PhD, FAHA; Junxiu Liu, PhD; Matthew Shane Loop, PhD, FAHA; Jun Ma, MD, PhD, FAHA; Michael E. Mussolino, PhD, FAHA; Sankar D. Navaneethan, MD, MS, MPH; Amanda Marma Perak, MD, MS, FAHA; Remy Poudel, MS, MPH, CPH; Mary Rezk-Hanna, PhD, FAHA; Gregory A. Roth, MD, MPH, FAHA; Emily B. Schroeder, MD, PhD, FAHA; Svati H. Shah, MD, MHS, FAHA; Evan L. Thacker, PhD; Lisa B. VanWagner, MD, MSc,